Floy Agnes Lee was a technician who worked on the Manhattan Project, which was the American-led effort to build nuclear weapons during World War II. Her father was part of the Santa Clara Pueblo and her mother was German-American. In 1945, she majored in biology from the University of New Mexico and was recruited to work at the hematology lab at Los Alamos. She examined blood samples to study the effect of radiation. After World War II ended, she continued her studies at the University of Chicago to earn a doctorate in biology. She worked at the Argonne National Laboratory, the Jet Propulsion Lab, and the Los Alamos National Laboratory. In 2018, she died at the age of 95.

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