Carolyn Bertozzi is an American chemist known for her wide-ranging work in both chemistry and biology. In 1999, while working with HHMI and at Berkeley, she founded the field of bioorthogonal chemistry, for which she shared the 2022 Nobel Prize in Chemistry with Morten Meldal and K. Barry Sharpless. This class of chemical reactions allows researchers to chemically modify molecules in living organisms and not disrupt the normal chemistry of the cell. These reactions are used to improve the targeting of cancer pharmaceuticals. In addition to the Nobel Prize, Bertozzi was named a MacArthur Fellow in 1999 and in 2010, she was the first woman to receive the prestigious Lemelson–MIT Prize faculty award.
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